Ultrafast Microvessel Imaging

Ultrasensitive, ultrafast microvessel imaging without contrast microbubbles:

Related publications:

  1. Song P, Manduca A, Trzasko JD, Chen S, “Letters: Noise Equalization for Ultrafast Plane Wave Microvessel Imaging,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 64, issue 11, pp. 1776-1781, 2017. PDF
  2. Gong P, Song P, Chen S, “Ultrafast Synthetic Transmit Aperture Imaging (USTA) Using Hadamard-Encoded Virtual Sources with Overlapping Sub-Apertures,” IEEE Transactions on Medical Imaging, vol. 36, no. 6, pp. 1372-1381, 2017. PDF
  3. Song P, Trzasko JD, Manduca A, Qiang B, Kadirvel R, Kallmes DF, Chen S, “Accelerated Singular Value-Based Ultrasound Blood Flow Clutter Filtering with Randomized Singular Value Decomposition (rSVD) and Randomized Spatial Downsampling,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 64, no. 4, pp. 706-716, 2017. PDF
  4. Song P, Manduca A, Trzasko JD, Chen S, “Ultrasound Small Vessel Imaging with Block-wise Adaptive Local Clutter Filtering,” IEEE Transactions on Medical Imaging, vol. 36, no. 1, pp. 251-262, 2017. PDF
  5. Huang C, Lowerison MR (co-first author), Lucien F, Wang D, Gong P, Song P (co-corresponding), Chen S, “Noninvasive Contrast-Free 3D Evaluation of Tumor Angiogenesis with Ultrasensitive Ultrasound Microvessel Imaging,” Scientific Reports, vol. 9, no. 1, pp. 4907, 2019. PDF
  6. Huang C, Song P, Gong P, Trzasko JD, Manduca A, Chen S*, “Debiasing-based Noise Suppression for Ultrafast Ultrasound Microvessel Imaging,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 66, no. 8, pp. 1281-1291, 2019. (PDF)
  7. Gong P†, Song P†, Huang C, Fazzio RT, Ruddy KJ, Ghosh K, Meixner DD, Ling W*, Chen S, “Ultra-sensitive Ultrasound Microvessel Imaging for Characterizing Benign and Malignant Breast Tumors,” Ultrasound in Medicine and Biology, vol. 45, issue 12, pp. 3128-3136, 2019. PDF
  8. Gong P†, Song P†, Kolbe AB, Sheedy SP, Huang C, Ling W, Yu Y, Lok UW, Tang S, Knudsen JM, Bruining DH, Chen S*, “Quantitative Inflammation Assessment of Inflammatory Bowel Disease Using Ultrafast Ultrasound Microvessel Imaging: A Pilot Study” Journal of Ultrasound in Medicine, 39:1819-1827, 2020. PDF
  9. Lok UW, Song P, Trzasko JD, Daigle RE, Borisch EA, Huang C, Gong P, Ling W, Chen S*, “Real time SVD-based clutter filtering using randomized singular value decomposition and spatial downsampling for micro-vessel imaging on a Verasonics system”, Ultrasonics, vol. 107, 106163, pp. 1-11, 2020. PDF

Grant support:

  1. K99/R00CA214523 from the National Cancer Institute (NCI) of the National Institutes of Health (NIH).
  2. Breast Cancer Research Program (BCRP) Breakthrough Award (E01 W81XWH2110062) from the Department of Defense (DoD) office of the Congressionally Directed Medical Research Program (CDMRP)